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SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment

Most tumors initially respond to cytotoxic treatments, but acquired resistance often follows. The tumor microenvironment (TME) is a major barrier to clinical success by compromising therapeutic efficacy, and pathological relevance of multiple soluble factors released by a therapeutically remodeled T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Sun, Y, Zhu, D, Chen, F, Qian, M, Wei, H, Chen, W, Xu, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994019/
https://ncbi.nlm.nih.gov/pubmed/26751775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.494
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