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Non-ribosomal Peptide Extension by a Peptide Amino-acyl tRNA Ligase

The catalytic use of a small peptide scaffold for the biosynthesis of amino acid-derived natural products is a recently discovered new biosynthetic strategy. During this process, a peptide-amino acyl tRNA ligase (PEARL), adds amino acids to the C-terminus of a small peptide scaffold in an ATP and tR...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Zhang, Zhengan, van der Donk, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927032/
https://ncbi.nlm.nih.gov/pubmed/31751505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07111
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