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Post-translational Introduction of d-Alanine into Ribosomally Synthesized Peptides by the Dehydroalanine Reductase NpnJ
[Image: see text] Ribosomally synthesized peptides are generally limited to l-amino acid building blocks. Given the advantageous properties of peptides containing d-amino acids such as stabilization of certain turns and against proteolytic degradation, methods to introduce d-stereocenters are valuab...
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| Pubblicato in: | J Am Chem Soc |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2015
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599312/ https://ncbi.nlm.nih.gov/pubmed/26361061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05207 |
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