Endoplasmic reticulum stress differentially inhibits endoplasmic reticulum and inner nuclear membrane protein quality control degradation pathways

Endoplasmic reticulum (ER) stress occurs when the abundance of unfolded proteins in the ER exceeds the capacity of the folding machinery. Despite the expanding cadre of characterized cellular adaptations to ER stress, knowledge of the effects of ER stress on cellular physiology remains incomplete. W...

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Publicado en:J Biol Chem
Autores principales: Buchanan, Bryce W., Mehrtash, Adrian B., Broshar, Courtney L., Runnebohm, Avery M., Snow, Brian J., Scanameo, Laura N., Hochstrasser, Mark, Rubenstein, Eric M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926463/
https://ncbi.nlm.nih.gov/pubmed/31723032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010295
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