Endoplasmic reticulum stress differentially inhibits endoplasmic reticulum and inner nuclear membrane protein quality control degradation pathways

Endoplasmic reticulum (ER) stress occurs when the abundance of unfolded proteins in the ER exceeds the capacity of the folding machinery. Despite the expanding cadre of characterized cellular adaptations to ER stress, knowledge of the effects of ER stress on cellular physiology remains incomplete. W...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Buchanan, Bryce W., Mehrtash, Adrian B., Broshar, Courtney L., Runnebohm, Avery M., Snow, Brian J., Scanameo, Laura N., Hochstrasser, Mark, Rubenstein, Eric M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Protein Synthesis and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926463/
https://ncbi.nlm.nih.gov/pubmed/31723032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010295
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