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Collagen receptor cross-talk determines α-smooth muscle actin-dependent collagen gene expression in angiotensin II–stimulated cardiac fibroblasts

Excessive collagen deposition by myofibroblasts during adverse cardiac remodeling leads to myocardial fibrosis that can compromise cardiac function. Unraveling the mechanisms underlying collagen gene expression in cardiac myofibroblasts is therefore an important clinical goal. The collagen receptors...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: V, Harikrishnan, Titus, Allen Sam, Cowling, Randy T., Kailasam, Shivakumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926455/
https://ncbi.nlm.nih.gov/pubmed/31699892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009744
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