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The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling

Cardiac myofibroblasts play an important role in myocardial remodeling. Although α-smooth muscle actin (α-SMA) expression is the hallmark of mature myofibroblasts, its role in regulating fibroblast function remains poorly understood. We explore the effects of the matrix environment in modulating car...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Shinde, Arti V, Humeres, Claudio, Frangogiannis, Nikolaos G
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5163362/
https://ncbi.nlm.nih.gov/pubmed/27825850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.11.006
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