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Template-switching mechanism of a group II intron-encoded reverse transcriptase and its implications for biological function and RNA-Seq

The reverse transcriptases (RTs) encoded by mobile group II introns and other non-LTR retroelements differ from retroviral RTs in being able to template-switch efficiently from the 5′ end of one template to the 3′ end of another with little or no complementarity between the donor and acceptor templa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lentzsch, Alfred M., Yao, Jun, Russell, Rick, Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926447/
https://ncbi.nlm.nih.gov/pubmed/31712313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011337
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