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Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications

Bacterial group II intron reverse transcriptases (RTs) function in both intron mobility and RNA splicing and are evolutionary predecessors of retrotransposon, telomerase, and retroviral RTs, as well as spliceosomal protein Prp8 in eukaryotes. Here, we determined a crystal structure of a full-length...

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書誌詳細
出版年:Mol Cell
主要な著者: Stamos, Jennifer L., Lentzsch, Alfred M., Lambowitz, Alan M.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728383/
https://ncbi.nlm.nih.gov/pubmed/29153391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.024
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