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rAAV2-Retro Enables Extensive and High-Efficient Transduction of Lower Motor Neurons following Intramuscular Injection

The motor system controls muscle movement through lower motor neurons in the spinal cord and brainstem. Lower motor neurons are efferent neurons in the central nervous system (CNS) characterized by axonal projections that reach specific targets in the periphery. Lower motor neuron lesions result in...

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Bibliografske podrobnosti
izdano v:Mol Ther Methods Clin Dev
Main Authors: Chen, Zhilong, Fan, Guoqing, Li, Anan, Yuan, Jing, Xu, Tonghui
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926343/
https://ncbi.nlm.nih.gov/pubmed/31890738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.11.006
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