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rAAV2-Retro Enables Extensive and High-Efficient Transduction of Lower Motor Neurons following Intramuscular Injection

The motor system controls muscle movement through lower motor neurons in the spinal cord and brainstem. Lower motor neurons are efferent neurons in the central nervous system (CNS) characterized by axonal projections that reach specific targets in the periphery. Lower motor neuron lesions result in...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Chen, Zhilong, Fan, Guoqing, Li, Anan, Yuan, Jing, Xu, Tonghui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926343/
https://ncbi.nlm.nih.gov/pubmed/31890738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.11.006
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