Anti-CD20 therapy depletes activated myelin-specific CD8(+) T cells in multiple sclerosis

CD8(+) T cells are believed to play an important role in multiple sclerosis (MS), yet their role in MS pathogenesis remains poorly defined. Although myelin proteins are considered potential autoantigenic targets, prior studies of myelin-reactive CD8(+) T cells in MS have relied on in vitro stimulati...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Sabatino, Joseph J., Wilson, Michael R., Calabresi, Peter A., Hauser, Stephen L., Schneck, Jonathan P., Zamvil, Scott S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926057/
https://ncbi.nlm.nih.gov/pubmed/31748274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915309116
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