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Ocrelizumab and Other CD20(+) B-Cell-Depleting Therapies in Multiple Sclerosis

Selective depletion of CD20(+) B cells by anti-CD20 monoclonal antibodies as monotherapy in multiple sclerosis (MS) profoundly suppresses acute inflammatory disease activity and signifies an important advance in the treatment of relapsing-remitting MS. Ocrelizumab, a humanized anti-CD20 monoclonal a...

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Publicado en:Neurotherapeutics
Main Authors: Gelfand, Jeffrey M., Cree, Bruce A. C., Hauser, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722762/
https://ncbi.nlm.nih.gov/pubmed/28695471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-017-0557-4
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