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Anti-CD20 therapy depletes activated myelin-specific CD8(+) T cells in multiple sclerosis
CD8(+) T cells are believed to play an important role in multiple sclerosis (MS), yet their role in MS pathogenesis remains poorly defined. Although myelin proteins are considered potential autoantigenic targets, prior studies of myelin-reactive CD8(+) T cells in MS have relied on in vitro stimulati...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926057/ https://ncbi.nlm.nih.gov/pubmed/31748274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915309116 |
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