Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy

BACKGROUND: Myopathy and exercise intolerance are prominent clinical features in carriers of a point-mutation or large-scale deletion in the mitochondrial DNA (mtDNA). In the majority of patients, the mtDNA mutation is heteroplasmic with varying mutation loads between tissues of an individual. Exerc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: van Tienen, Florence, Zelissen, Ruby, Timmer, Erika, van Gisbergen, Marike, Lindsey, Patrick, Quattrocelli, Mattia, Sampaolesi, Maurilio, Mulder-den Hartog, Elvira, de Coo, Irenaeus, Smeets, Hubert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925445/
https://ncbi.nlm.nih.gov/pubmed/31864395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1510-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados