Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation

Mitochondria are essential organelles whose function is upheld by their dynamic nature. This plasticity is mediated by large dynamin-related GTPases, called mitofusins in the case of fusion between two mitochondrial outer membranes. Fusion requires ubiquitylation, attached to K398 in the yeast mitof...

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Vydáno v:Life Sci Alliance
Hlavní autoři: Schuster, Ramona, Anton, Vincent, Simões, Tânia, Altin, Selver, den Brave, Fabian, Hermanns, Thomas, Hospenthal, Manuela, Komander, David, Dittmar, Gunnar, Dohmen, R Jürgen, Escobar-Henriques, Mafalda
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2019
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925385/
https://ncbi.nlm.nih.gov/pubmed/31857350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900476
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