Dusp8 affects hippocampal size and behavior in mice and humans

Dual-specificity phosphatase 8 (Dusp8) acts as physiological inhibitor for the MAPKs Jnk, Erk and p38 which are involved in regulating multiple CNS processes. While Dusp8 expression levels are high in limbic areas such as the hippocampus, the functional role of Dusp8 in hippocampus morphology, MAPK-...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Baumann, Peter, Schriever, Sonja C., Kullmann, Stephanie, Zimprich, Annemarie, Feuchtinger, Annette, Amarie, Oana, Peter, Andreas, Walch, Axel, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Wurst, Wolfgang, Tschöp, Matthias H., Heni, Martin, Hölter, Sabine M., Pfluger, Paul T.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925303/
https://ncbi.nlm.nih.gov/pubmed/31862894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55527-7
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