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Polyanions provide selective control of APC/C interactions with the activator subunit
Transient interactions between the anaphase-promoting complex/cyclosome (APC/C) and its activator subunit Cdc20 or Cdh1 generate oscillations in ubiquitylation activity necessary to maintain the order of cell cycle events. Activator binds the APC/C with high affinity and exhibits negligible dissocia...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6925294/ https://ncbi.nlm.nih.gov/pubmed/31862931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13864-1 |
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