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Biological Evaluation of Noscapine analogues as Potent and Microtubule-Targeted Anticancer Agents
In present investigation, an attempt was undertaken to modify the C-9 position of noscapine (Nos), an opium alkaloid to yield 9 -hydroxy methyl and 9 -carbaldehyde oxime analogues for augmenting anticancer potential. The synthesis of 9-hydroxy methyl analogue of Nos was carried out by Blanc reaction...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6925231/ https://ncbi.nlm.nih.gov/pubmed/31862933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55839-8 |
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