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Mechanistic Interaction Study of Bromo-Noscapine with Bovine Serum Albumin employing Spectroscopic and Chemoinformatics Approaches

Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity against breast and lung cancer. The mechanistic interaction insight into the binding of bovine serum albumin (BSA) with BrNs can provide critical information about the pharmacodynamics and pharmacokinetics properti...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Sood, Damini, Kumar, Neeraj, Rathee, Garima, Singh, Anju, Tomar, Vartika, Chandra, Ramesh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240080/
https://ncbi.nlm.nih.gov/pubmed/30446713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35384-6
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