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Mechanistic Interaction Study of Bromo-Noscapine with Bovine Serum Albumin employing Spectroscopic and Chemoinformatics Approaches

Bromo-Noscapine (BrNs) is a tubulin-binding cytotoxic agent with significant activity against breast and lung cancer. The mechanistic interaction insight into the binding of bovine serum albumin (BSA) with BrNs can provide critical information about the pharmacodynamics and pharmacokinetics properti...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Sood, Damini, Kumar, Neeraj, Rathee, Garima, Singh, Anju, Tomar, Vartika, Chandra, Ramesh
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240080/
https://ncbi.nlm.nih.gov/pubmed/30446713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35384-6
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