Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases

Aging is associated with increased oxidative stress in vascular endothelial and smooth muscle cells, which contribute to the development of a wide range of diseases affecting the circulatory system in older adults. There is growing evidence that in addition to increased production of reactive oxygen...

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Bibliographic Details
Published in:GeroScience
Main Authors: Ungvari, Zoltan, Tarantini, Stefano, Nyúl-Tóth, Ádám, Kiss, Tamas, Yabluchanskiy, Andriy, Csipo, Tamas, Balasubramanian, Priya, Lipecz, Agnes, Benyo, Zoltan, Csiszar, Anna
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925097/
https://ncbi.nlm.nih.gov/pubmed/31655958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00107-w
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