Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

Aging-induced pro-inflammatory phenotypic alterations of the cerebral vasculature critically contribute to the pathogenesis of vascular cognitive impairment. Cellular senescence is a fundamental aging process that promotes inflammation; however, its role in cerebrovascular aging remains unexplored....

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Vydáno v:GeroScience
Hlavní autoři: Fulop, Gabor A., Kiss, Tamas, Tarantini, Stefano, Balasubramanian, Priya, Yabluchanskiy, Andriy, Farkas, Eszter, Bari, Ferenc, Ungvari, Zoltan, Csiszar, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294722/
https://ncbi.nlm.nih.gov/pubmed/30470983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0047-6
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