EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma

Targeting solid tumor antigens with chimeric antigen receptor (CAR) T cell therapy requires tumor specificity and tolerance toward variability in antigen expression levels. Given the relative paucity of unique cell surface proteins on tumor cells for CAR targeting, we have focused on identifying tum...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ravanpay, Ali C., Gust, Juliane, Johnson, Adam J., Rolczynski, Lisa S., Cecchini, Michelle, Chang, Cindy A., Hoglund, Virginia J., Mukherjee, Rithun, Vitanza, Nicholas A., Orentas, Rimas J., Jensen, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925027/
https://ncbi.nlm.nih.gov/pubmed/31903167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27389
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