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Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob disease (vCJD) is caused by prion infection with bovine spongiform encephalopathy and can be transmitted by blood transfusion. Protein misfolding cyclic amplification (PMCA) can detect prions in blood from vCJD patients with 100% sensitivity and specificity. To determine wh...

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Detalles Bibliográficos
Publicado en:Emerg Infect Dis
Main Authors: Concha-Marambio, Luis, Chacon, Marcelo A., Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado: Centers for Disease Control and Prevention 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924915/
https://ncbi.nlm.nih.gov/pubmed/31855141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2601.181423
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