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Development of Dose-Response Models of Creutzfeldt-Jakob Disease Infection in Nonhuman Primates for Assessing the Risk of Transfusion-Transmitted Variant Creutzfeldt-Jakob Disease

Estimates for the risk of transmitting variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion have relied largely on data from rodent experiments, but the relationship between dose (amount of infected blood) and response (vCJD infection) has never been well quantified. The goal of this study...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Huang, Yin, Gregori, Luisa, Anderson, Steven A., Asher, David M., Yang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248962/
https://ncbi.nlm.nih.gov/pubmed/25231313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01805-14
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