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Management of toxicity to isoform α-specific PI3K inhibitors

Alterations in the phosphoinositide 3-kinase (PI3K)/AKT pathway are frequently found in cancer and are especially common in breast cancer, where it is estimated that 70% of tumors have some type of genetic alteration that could lead to pathway hyperactivation. A variety of PI3K pathway inhibitors ha...

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Detalhes bibliográficos
Publicado no:Ann Oncol
Main Authors: Nunnery, S E, Mayer, I A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923786/
https://ncbi.nlm.nih.gov/pubmed/31626273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdz440
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