The RAB3-RIM pathway is essential for the release of neuromodulators

Secretion principles are conserved from yeast to humans and many yeast orthologs have established roles in synaptic vesicle exocytosis in the mammalian brain. Surprisingly, SEC4 orthologues and their effectors, the exocyst, are dispensable for synaptic vesicle exocytosis. Here, we identify the SEC4...

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Bibliografiske detaljer
Udgivet i:	Neuron
Main Authors:	Persoon, Claudia M., Hoogstraaten, Rein, Nassal, Joris P., van Weering, Jan R.T., Kaeser, Pascal S., Toonen, Ruud F., Verhage, Matthijs
Format:	Artigo
Sprog:	Inglês
Udgivet:	2019
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6923582/ https://ncbi.nlm.nih.gov/pubmed/31679900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.09.015
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The RAB3-RIM pathway is essential for the release of neuromodulators

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