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Neuromodulator release in neurons requires two functionally redundant calcium sensors
Neuropeptides and neurotrophic factors secreted from dense core vesicles (DCVs) control many brain functions, but the calcium sensors that trigger their secretion remain unknown. Here, we show that in mouse hippocampal neurons, DCV fusion is strongly and equally reduced in synaptotagmin-1 (Syt1)- or...
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| Foilsithe in: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8106342/ https://ncbi.nlm.nih.gov/pubmed/33903230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012137118 |
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