The RAB3-RIM pathway is essential for the release of neuromodulators

Secretion principles are conserved from yeast to humans and many yeast orthologs have established roles in synaptic vesicle exocytosis in the mammalian brain. Surprisingly, SEC4 orthologues and their effectors, the exocyst, are dispensable for synaptic vesicle exocytosis. Here, we identify the SEC4...

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Publicado en:Neuron
Main Authors: Persoon, Claudia M., Hoogstraaten, Rein, Nassal, Joris P., van Weering, Jan R.T., Kaeser, Pascal S., Toonen, Ruud F., Verhage, Matthijs
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923582/
https://ncbi.nlm.nih.gov/pubmed/31679900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.09.015
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