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Single-cell profiles of retinal ganglion cells differing in resilience to injury reveal neuroprotective genes

Neuronal types in the central nervous system differ dramatically in their resilience to injury or insults. Here we studied the selective resilience of mouse retinal ganglion cells (RGCs) following optic nerve crush (ONC), which severs their axons and leads to death of ~80% of RGCs within 2 weeks. To...

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מידע ביבליוגרפי
הוצא לאור ב:	Neuron
Main Authors:	Tran, Nicholas M., Shekhar, Karthik, Whitney, Irene E., Jacobi, Anne, Benhar, Inbal, Hong, Guosong, Yan, Wenjun, Adiconis, Xian, Arnold, McKinzie E., Lee, Jung Min, Levin, Joshua Z., Lin, Dingchang, Wang, Chen, Lieber, Charles M., Regev, Aviv, He, Zhigang, Sanes, Joshua R.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2019
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6923571/ https://ncbi.nlm.nih.gov/pubmed/31784286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.11.006
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Single-cell profiles of retinal ganglion cells differing in resilience to injury reveal neuroprotective genes

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