Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis

Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent eye disease characterized by death of retinal ganglion cells; lowering IOP is the only proven treatment strategy to delay disease progression. The main determinant of IOP is the equilibrium between producti...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: van Zyl, Tavé, Yan, Wenjun, McAdams, Alexi, Peng, Yi-Rong, Shekhar, Karthik, Regev, Aviv, Juric, Dejan, Sanes, Joshua R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229661/
https://ncbi.nlm.nih.gov/pubmed/32341164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001250117
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