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Fractional Laser-Mediated siRNA Delivery for Mitigating Psoriasis-like Lesions via IL-6 Silencing
The poor permeability of topically applied macromolecules such as small interfering RNA (siRNA) has inhibited the translation to clinical application. In this study, the fractional CO(2) laser-assisted approach was developed to describe siRNA permeation enhancement mediated by the created microchann...
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| Publicado en: | Mol Ther Nucleic Acids |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923496/ https://ncbi.nlm.nih.gov/pubmed/31855833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.11.013 |
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