Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis

Myocarditis is an inflammatory disease of the heart muscle most commonly caused by viral infection and often maintained by autoimmunity. Virus-induced tissue damage triggers chemokine production and, subsequently, immune cell infiltration with pro-inflammatory and pro-fibrotic cytokine production fo...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Meyer, Ingmar Sören, Goetzke, Carl Christoph, Kespohl, Meike, Sauter, Martina, Heuser, Arnd, Eckstein, Volker, Vornlocher, Hans-Peter, Anderson, Daniel G., Haas, Jan, Meder, Benjamin, Katus, Hugo Albert, Klingel, Karin, Beling, Antje, Leuschner, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186826/
https://ncbi.nlm.nih.gov/pubmed/30349538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02303
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