Helix 8 is the essential structural motif of mechanosensitive GPCRs

G-protein coupled receptors (GPCRs) are versatile cellular sensors for chemical stimuli, but also serve as mechanosensors involved in various (patho)physiological settings like vascular regulation, cardiac hypertrophy and preeclampsia. However, the molecular mechanisms underlying mechanically induce...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Erdogmus, Serap, Storch, Ursula, Danner, Laura, Becker, Jasmin, Winter, Michaela, Ziegler, Nicole, Wirth, Angela, Offermanns, Stefan, Hoffmann, Carsten, Gudermann, Thomas, Mederos y Schnitzler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923424/
https://ncbi.nlm.nih.gov/pubmed/31857598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13722-0
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