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Dynamic monitoring of G(i/o)-protein-mediated decreases of intracellular cAMP by FRET-based Epac sensors
Analysis of G-protein-coupled receptor (GPCR) signaling, in particular of the second messenger cAMP that is tightly controlled by G(s)- and G(i/o)-proteins, is a central issue in biomedical research. The classical biochemical method to monitor increases in intracellular cAMP concentrations consists...
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| Publicado no: | Pflugers Arch |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438440/ https://ncbi.nlm.nih.gov/pubmed/28386636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-017-1975-1 |
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