Guanosine and GMP increase the number of granular cerebellar neurons in culture: dependence on adenosine A(2A) and ionotropic glutamate receptors

The guanine-based purines (GBPs) have essential extracellular functions such as modulation of glutamatergic transmission and trophic effects on neurons and astrocytes. We previously showed that GBPs, such as guanosine-5′-monophosphate (GMP) or guanosine (GUO), promote the reorganization of extracell...

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Pubblicato in:Purinergic Signal
Autori principali: Decker, Helena, Piermartiri, Tetsade C. B., Nedel, Cláudia B., Romão, Luciana F., Francisco, Sheila S., Dal-Cim, Tharine, Boeck, Carina R., Moura-Neto, Vivaldo, Tasca, Carla I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923314/
https://ncbi.nlm.nih.gov/pubmed/31478180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09677-y
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