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Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A(1) and A(2A) adenosine receptors and PI3K, MEK, and PKC pathways

Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue viability during ischemia, and astrocytes are the main source of extracellular purines as adenosine and guanosine. The endogenous guanine-based nucleoside guanosine is a neuromodulator implicated in import...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Purinergic Signal
मुख्य लेखकों: Dal-Cim, Tharine, Poluceno, Gabriela G., Lanznaster, Débora, de Oliveira, Karen A., Nedel, Claudia B., Tasca, Carla I.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer Netherlands 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923312/
https://ncbi.nlm.nih.gov/pubmed/31520282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09679-w
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