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Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A(1) and A(2A) adenosine receptors and PI3K, MEK, and PKC pathways
Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue viability during ischemia, and astrocytes are the main source of extracellular purines as adenosine and guanosine. The endogenous guanine-based nucleoside guanosine is a neuromodulator implicated in import...
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| Publicado no: | Purinergic Signal |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923312/ https://ncbi.nlm.nih.gov/pubmed/31520282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09679-w |
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