Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation

Guanosine, the endogenous guanine nucleoside, prevents cellular death induced by ischemic events and is a promising neuroprotective agent. During an ischemic event, nitric oxide has been reported to either cause or prevent cell death. Our aim was to evaluate the neuroprotective effects of guanosine...

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Publicat a:Purinergic Signal
Autors principals: Thomaz, Daniel T., Dal-Cim, Tharine A., Martins, Wagner C., Cunha, Maurício Peña, Lanznaster, Débora, de Bem, Andreza F., Tasca, Carla I.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124011/
https://ncbi.nlm.nih.gov/pubmed/27613537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9534-3
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