A Strong Decrease in TIMP3 Expression Mediated by the Presence of miR-17 and 20a Enables Extracellular Matrix Remodeling in the NSCLC Lesion Surroundings

Background: Lung cancer is one of the most common causes of death worldwide with a relatively high fatality rate and a mean 5-years survival of about 18%. One of the hallmarks of cancer is the extracellular matrix (ECM) remodeling, which is crucial for metastasis. This process may be regulated by mi...

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Опубликовано в: :Front Oncol
Главные авторы: Czarnecka, Karolina H., Szmyd, Bartosz, Barańska, Magda, Kaszkowiak, Marcin, Kordiak, Jacek, Antczak, Adam, Pastuszak-Lewandoska, Dorota, Brzeziańska-Lasota, Ewa
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923190/
https://ncbi.nlm.nih.gov/pubmed/31921636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01372
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