Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis

The aim of the study was to investigate the influence of allelic imbalance (AI) in several loci of tumor suppressor genes in 3p region on the non-small cell lung cancer (NSCLC) development. We evaluated the frequency of loss of heterozygosity and/or microsatellite imbalance (LOH/MSI) and assessed th...

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Bibliographic Details
Main Authors: Antczak, Adam, Migdalska-Sęk, Monika, Pastuszak-Lewandoska, Dorota, Czarnecka, Karolina, Nawrot, Ewa, Domańska, Daria, Kordiak, Jacek, Górski, Paweł, Brzeziańska, Ewa
Format: Artigo
Language:Inglês
Published: Springer US 2013
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667378/
https://ncbi.nlm.nih.gov/pubmed/23504373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-013-0532-9
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