Quantitative analysis of mRNA expression levels and DNA methylation profiles of three neighboring genes: FUS1, NPRL2/G21 and RASSF1A in non-small cell lung cancer patients

BACKGROUND: Tumor suppressor gene (TSG) inactivation plays a crucial role in carcinogenesis. FUS1, NPRL2/G21 and RASSF1A are TSGs from LUCA region at 3p21.3, a critical chromosomal region in lung cancer development. The aim of the study was to analyze and compare the expression levels of these 3 TSG...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Pastuszak-Lewandoska, Dorota, Kordiak, Jacek, Migdalska-Sęk, Monika, Czarnecka, Karolina H., Antczak, Adam, Górski, Paweł, Nawrot, Ewa, Kiszałkiewicz, Justyna M., Domańska, Daria, Brzeziańska-Lasota, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484633/
https://ncbi.nlm.nih.gov/pubmed/26112163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0230-6
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