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Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models

Biochemical gradients across the intestinal epithelium play a major role in governing intestinal stem cell compartmentalization, differentiation dynamics, and organ-level self-renewal. However, scalable platforms that recapitulate the architecture and gradients present in vivo are absent. We present...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Hinman, Samuel S., Wang, Yuli, Allbritton, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6923129/
https://ncbi.nlm.nih.gov/pubmed/31692334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b04217
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