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Optimization of 3-D organotypic primary colonic cultures for organ-on-chip applications

BACKGROUND: New advances enable long-term organotypic culture of colonic epithelial stem cells that develop into structures known as colonoids. Colonoids represent a primary tissue source acting as a potential starting material for development of an in vitro model of the colon. Key features of colon...

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Autors principals: Ahmad, Asad A, Wang, Yuli, Gracz, Adam D, Sims, Christopher E, Magness, Scott T, Allbritton, Nancy L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022271/
https://ncbi.nlm.nih.gov/pubmed/24690469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-8-9
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