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Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer

BACKGROUND & AIMS: The successful culture of intestinal organoids has greatly enhanced our understanding of intestinal stem cell physiology and enabled the generation of novel intestinal disease models. Although of tremendous value, intestinal organoid culture systems have not yet fully recapitu...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Wang, Yuli, Kim, Raehyun, Gunasekara, Dulan B., Reed, Mark I., DiSalvo, Matthew, Nguyen, Daniel L., Bultman, Scott J., Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904049/
https://ncbi.nlm.nih.gov/pubmed/29693040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.10.007
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