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Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics

Pluripotent stem cells retain the developmental timing of their species of origin in vitro, an observation that suggests the existence of a cell-intrinsic developmental clock, yet the nature and machinery of the clock remain a mystery. We hypothesize that one possible component may lie in species-sp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Comput Biol
मुख्य लेखकों: Barry, Christopher, Schmitz, Matthew T., Argus, Cara, Bolin, Jennifer M., Probasco, Mitchell D., Leng, Ning, Duffin, Bret M., Steill, John, Swanson, Scott, McIntosh, Brian E., Stewart, Ron, Kendziorski, Christina, Thomson, James A., Bacher, Rhonda
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922475/
https://ncbi.nlm.nih.gov/pubmed/31815944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007543
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