Klebsiella pneumoniae Expressing VIM-1 Metallo-β-Lactamase Is Resensitized to Cefotaxime via Thiol-Mediated Zinc Chelation

Antibiotic-resistant Klebsiella pneumoniae isolates constitute a great clinical challenge. One important resistance mechanism in K. pneumoniae is the metallo-β-lactamases (MBLs), which require zinc for their function. Thus, zinc chelation could be a strategy to resensitize K. pneumoniae to β-lactams...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Karadottir, Harpa, Coorens, Maarten, Liu, Zhihai, Wang, Yang, Agerberth, Birgitta, Giske, Christian G., Bergman, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921649/
https://ncbi.nlm.nih.gov/pubmed/31611270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00756-19
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados