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Synthesis and Characterization of a Click-Assembled 18-Atom Macrocycle That Displays Selective AXL Kinase Inhibitory Activity
[Image: see text] A novel macrocyclic construct consisting of a pyrazolopyrimidine scaffold concatenated to a benzene ring through two triazoles has been developed to investigate uncharted chemical space with bioactive potential. The 18-atom macrocycle was assembled via a double copper-catalyzed alk...
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| Pubblicato in: | ACS Omega |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2019
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6921642/ https://ncbi.nlm.nih.gov/pubmed/31867559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03525 |
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