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Targeting cancers through TCR-peptide/MHC interactions

Adoptive T cell therapy has achieved dramatic success in a clinic, and the Food and Drug Administration approved two chimeric antigen receptor-engineered T cell (CAR-T) therapies that target hematological cancers in 2018. A significant issue faced by CAR-T therapies is the lack of tumor-specific bio...

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Detalles Bibliográficos
Publicado en:J Hematol Oncol
Main Authors: He, Qinghua, Jiang, Xianhan, Zhou, Xinke, Weng, Jinsheng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921533/
https://ncbi.nlm.nih.gov/pubmed/31852498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0812-8
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