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Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration

Microglia play an essential role for central nervous system (CNS) development and homeostasis and have been implicated in the onset, progression, and clearance of numerous diseases affecting the CNS. Previous in vitro research on human microglia was restricted to post-mortem brain tissue-derived mic...

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Bibliografske podrobnosti
izdano v:Mol Neurodegener
Main Authors: Speicher, Anna M., Wiendl, Heinz, Meuth, Sven G., Pawlowski, Matthias
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921408/
https://ncbi.nlm.nih.gov/pubmed/31856864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0347-z
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