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High-Fidelity Modeling of Human Microglia with Pluripotent Stem Cells

Gosselin et al. (2017) reported that a tissue-environment-dependent transcriptional network specifies human microglia identity and that in vitro environments drastically alter the human microglia transcriptome. Recent 3-dimensional culture and human-mouse chimeric brain modeling systems developed us...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Jiang, Peng, Turkalj, Luka, Xu, Ranjie
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262396/
https://ncbi.nlm.nih.gov/pubmed/32386554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.04.004
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